Towards Quantitative ICG Angiography: Fluorescence Monte Carlo Multi Cylinder
نویسندگان
چکیده
Abstract Intraoperative blood flow measurement is an effective way to assess the quality of bypass surgery. Flow quantification from indocyanine green (ICG) angiography promises be easy, contact-free method. It shows deviations compared a reference. These are given as factor k, which depends on vessel diameter d. The radiation transport within while recording ICG passage might cause this. analyzed in silico disclose its impact k (d). A Fluorescence Monte Carlo Multi Cylinder (FMCMC) model was developed static model, assuming homogeneous concentration ICG. In contrast published approaches utilizing Layer (MCML) deepest penetration location photon packet’s path fluorescence location, events modeled. event modeling, geometry and illumination well combinations these were implemented separate aspect models. Resulting (d) MCML. Deviations derived FMCMC MCML each present. Root Mean Square Error ranges 6,8% 36 %, also varied comparing models other. geometry, modeled mode show clear simulated Therefore, our study that simplifications previous studies invalid. considers named aspects, allowing analysis angiography. assumes not true clinical cases. Obtaining heterogeneous distribution possible via fluid Coupling including detailed camera optic task for future work.
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ژورنال
عنوان ژورنال: Current Directions in Biomedical Engineering
سال: 2021
ISSN: ['2364-5504']
DOI: https://doi.org/10.1515/cdbme-2021-2067